December 16

Acid Suppression leading to B12 deficiency

B12 is a vitamin is either called cobalamin or cyanocobalamin and is essential for many important functions in the human body. It is most notable for maintaining proper cognitive health, red blood cells, and lowering a cardiovascular risk factor called Homocysteine. This week in the Journal of the American Medical Association, researchers found that patients who use proton pump inhibitors and H2 Blockers for over 2 years were at increased risk of vitamin B12 deficiency. Patients should discuss the risk and benefits of staying on acid blockers long term with their physician. Several heartburn issues are mitigated by lifestyle changes, weight loss, and dietary modification.

B12 is found in many animal products but is difficult for vegetarians and vegans to get in their diet. It also needs acid to get absorbed. Aging and medications such as acid blockers, certain antibiotics, and certain hypoglycemic agents are few of the medications which block B12 absorption. Some symptoms of B12 deficiency are memory loss, mood changes, fatigue, irritability, numbness, and sore tongue.


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